What it's known for: Located in an 1800s brick building, Amen Street revives the historic name for the centuries-old street. The restaurant has an awesome raw bar, where the fish and oyster menu changes daily. The large, comfy booths are perfect for families, and the spot is a particularly good stop for lunch or happy hour.
What it's known for: Pitmaster Rodney Scott, winner of the James Beard 2018 Best Chef -- Southeast Award, is a legend in South Carolina and beyond. Famous for savory smoked whole hog, this barbecue joint is an offshoot of Scott's family business in Hemingway, where he smoked his first hog at age 11 using his "low and slow" technique. Ribs, chicken, catfish, mac and cheese, banana pudding and other Southern favorites are noteworthy as well.
Style: Barbecue, Southern, casual, James Beard award winner
What it's known for: Located on busy US 17 west of Charleston's historic district, this relaxed restaurant serves what it calls "soulful food." It's the place to teach your kids about deviled eggs, po' boy sandwiches and other seasonal Lowcountry fare. Don't miss the dessert board or the homemade ice cream.
What it's known for: Chef Sean Brock designed this restaurant to use only ingredients from the South. If it's not grown or caught here, it doesn't come into the kitchen. The menu changes daily, but some things appear often. Don't miss the crispy pig ear lettuce wraps, fried chicken skins, shrimp and grits or cult-favorite cheeseburger. A floor-to-ceiling chalkboard lists where all ingredients originate.
Style: Southern, farm-to-table, family-friendly, James Beard award winner
What it's known for: Grab a table outside and drink in the view. Situated on the Cooper River near Waterfront Park, this is the place to watch boats go by, marvel at the Ravenel Bridge and dine on traditional seafood dishes. You can see the USS Yorktown across the river and Fort Sumter in the distance. Great for families.
What it's known for: FIG stands for Food is Good, and that sums up everything that comes out of the kitchen here. Chef/partner Mike Lata works with local farmers and fishermen to showcase the best of the Lowcountry on each plate. This is a meal and place to remember.
What it's known for: Set in the elegant Belmond Charleston Place hotel, this standard-bearer for the Holy City is as welcoming as it is beautiful. Chef Michelle Weaver uses local ingredients to create innovative, memorable dishes. Enjoy a cocktail or glass of wine at the accompanying jazz bar, where the service shines as much as it does in the main dining room.
Style: Southern, Lowcountry, Elegant, James Beard Award Winner
What it's known for: Don't let SNOB's name fool you. It stands for Slightly North of Broad, but there's nothing snobby about this Port City standout. For more than two decades, SNOB has been combining locally grown vegetables, meats and seafood with Southern and French technique. Don't miss the shrimp and grits. They might just be the best in the city.
Style: Southern, Lowcountry, James Beard winner, traditional
What it's known for: Tucked away behind a beautiful wrought iron gate down a brick pathway just off Charleston's historic market, Peninsula Grill is one of the city's most romantic dining spots. Whether you choose the elegant dining room or lush courtyard, it's a remarkable setting for an exceptional meal. And don't miss the signature 12-layer Ultimate Coconut Cake, which is always on the menu.
What it's known for: Set in a building that was a restaurant and bar during the Revolutionary War, McCrady's combines the freshest local ingredients with the cutting edge culinary skills of chef Sean Brock for contemporary Southern dishes. The menu changes daily. Don't miss the hand-crafted cocktail list, which is filled with both classic and created drinks.
What it's known for: With a larger menu than some fine dining spots, High Cotton combines great local ingredients with expertise. It's a warm, inviting place that's also open for brunch. Don't miss the praline souffle. It takes a while to cook, so order it early.
What it's known for: The bone marrow bread pudding, the Mac burger and the Deckle, the most decadent, tasty part of the rib eye, have developed a loyal following here. Don't miss the Bacon Happy Hour, named appropriately after chef Jeremiah Bacon, who also is turning out seafood charcuterie from local waters as well as other innovative dishes.
What it's known for: This is the place to go for roasted oysters, Frogmore stew and fresh fried shrimp. Set on the marsh near Folly Beach, this James Beard American Classic restaurant is just that - a classic seafood joint. No trip to Charleston is complete without a visit.
Style: Classic, traditional, seafood, James Beard winner, Lowcountry, family-friendly, casual
What it's known for: "The Wreck," as it's known to locals, is named for a trawler that landed on the same spot in Shem Creek during Hurricane Hugo in 1989. And it's the place to get fried shrimp and other seafood. You'll snack on boiled peanuts while you're waiting.
What it's known for: Tucked away in a little pink building might just be the best fried chicken you'll ever taste. Martha Lou's has been serving up home-style, Southern soul food for more than 30 years. Come hungry because plates come with sides, and you can't leave without having some bread pudding.
What it's known for: Located in the midst of fertile farming community of Johns Island, The Fat Hen combines the best of local ingredients with French techniques. Don't miss their menu of specialty cocktails and local brews, as well as a divine Sunday brunch.
What it's known for: Chef Kevin Johnson uses seasonal ingredients from local farmers and fishermen to create his menu, and his in-house canning program keeps local wares available all year. The wood-burning oven contributes to the homey atmosphere. Don't miss the house-made charcuterie or great Sunday brunch.
What it's known for: This tiny spot brings big flavors, turning local ingredients into terrific Spanish, French and Italian dishes. The menu is the same for both lunch and dinner and changes each day, offering two appetizers, two entrees and two desserts.
What it's known for: The premiere Italian restaurant in the Lowcountry, chef Ken Vendrinski changes the menu daily to showcase the freshest local ingredients. Pasta is handmade each day and paired with local seafood in dishes you'll be talking about long after you leave.
What it's known for: Central Texas-style barbecue made its Charleston debut at this operation headed by famed pitmaster John Lewis. Belly up to the counter and order the smoked meat of your choice: pulled pork, turkey breast, house-made sausage (Texas hot guts) and melt-in-your-mouth brisket. Your order is cut in front of your eyes and served up with tantalizing sides like green chile corn pudding, collards and cowboy pinto beans.
What it's known for: The beer inspires the menu at this brew pub, where almost everything, including the extensive charcuterie program, is made from scratch. And it's almost as fun to read the beer menu as taste from it. The patio makes for a nice experience, and they serve Sunday brunch, too.
What it's known for: Regional Italian dishes sourced from local ingredients make this comfortable restaurant in lush farm country a must stop. House-made pasta and house-cured salumi shine here, as does whatever is growing in the fields nearby. Leave room for dessert for sure.
What it's known for: Best sandwich in Charleston? Check. Mike's Famous Duck Club is in a league of its own and has quite the following. There are other great choices too, plus do not miss the duck fat fries. Crazy good.
What it's known for: This is an old-style seafood house, complete with a big menu of fresh Lowcountry fare and a great view of Shem Creek. Fried shrimp shines here, but you can also get almost any traditional Charleston seafood dish. It's a great spot if you have a bigger party.